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Selected Publications

Caspari Thomas, 2016, Smoking may protect against Parkinson’s disease – but it’s more likely to kill you. The Conversation - 20 June 2016

Caspari Thomas, 2015, How cancer abducts your immune cells – and what we can do about it. The Conversation – 01/07/2015

Caspari Thomas and Hilditch Victoria, 2015, Two Distinct Cdc2 Pools Regulate Cell Cycle Progression and the DNA Damage Response in the Fission Yeast S.pombe. PLoS One. Jul 1;10(7):e0130748. doi: 10.1371

Mahyous Saeyd Salah Adam, Ewert-Krzemieniewska Katarzyna, Liu Boyin, Caspari Thomas, 2014, Hyperactive Cdc2 kinase interferes with the response to broken replication forks by trapping S.pombe Crb2 in its mitotic T215 phosphorylated state. Nucleic Acids Res. 2014;42(12):7734-7747.

Turner Thomas and Caspari Thomas, 2014, When heat casts a spell on the DNA damage checkpoints. Open Biol. 2014 Mar 12;4:140008.

Simon Janes, Ulrike Schmidt, Karim Ashour Garrido, Nadja Ney, Susanna Concilio, Mohamed Zekri, and Thomas Caspari, 2012, Heat induction of a novel Rad9 variant from a cryptic translation initiation site reduces mitotic commitment. J Cell Sci. 125 (Pt 19): 4487-4497.

Su-Jiun Lin, Christopher P. Wardlaw, Takashi Morishita, Charly Chahwan, Thomas Caspari, Ulrike Schmidt, Antony M. Carr and Valerie Garcia, 2012, The Rad4TopBP1 ATR-activation Domain Functions in G1/S phase in a Chromatin-Dependent Manner. PLOS Genetics, Jun;8(6):e1002801.

Furuya K, Poitelea M, Guo L, Caspari T and Carr AM, 2004, Chk1 activation requires Rad9 S/TQ-site phosphorylation to promote association with C-terminal BRCT domains of Rad4TOPBP1. Genes Dev. 18, 1154-1164.

Liu C, Powell KA, Mundt K, Wu L, Carr AM, Caspari T., 2003, Cop9/signalosome subunits and Pcu4 regulate ribonucleotide reductase by both checkpoint-dependent and -independent mechanisms Genes Dev. 17, 1130-1140.

Harris S, Kemplen C, Caspari T, Chan C, Lindsay HD, Poitelea M, Carr AM, and Price C., 2003,  Delineating the position of rad4+/cut5+ within the DNA-structure checkpoint pathways in Schizosaccharomyces pombe. J Cell Sci. 2003 Sep 1;116(Pt 17):3519-29.

Tomita K, Matsuura A, Caspari T, Carr AM, Akamatsu Y, Iwasaki H, Mizuno K, Ohta K, Uritani M, Ushimaru T, Yoshinaga K and Ueno M., 2003, Competition between the Rad50 complex and the Ku heterodimer reveals a role for Exo1 in processing double-strand breaks but not telomeres. Mol Cell Biol. 2003 Aug;23(15):5186-97.

Caspari T, Murray JM and Carr AM, 2002, Cdc2-cyclin B kinase activity links Crb2 and Rqh1-topoisomerase III. Genes Dev. 16(10), 1195-1208.

Caspari T and Carr AM, 2002 Checkpoints: how to flag up double-strand breaks. Curr Biol., 12, R105-107.

Caspari T, Dahlen M, Kanter-Smoler G, Lindsay HD, Hofmann K, Papadimitriou K, Sunnerhagen P and Carr AM, 2000,  Characterization of Schizosaccharomyces pombe Hus1: a PCNA-related protein that associates with Rad1 and Rad9. Mol Cell Biol. 2000 Feb;20(4):1254-62.

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